2-Benzyl-myo-inositol monohydrate

2-Benzyl-myo-inositol monohydrate

The title structure, C(13)H(18)O(6)·H(2)O, contains two independent 2-benzyl-myo-inositol and water mol-ecules. In the crystal, the mol-ecules are strongly hydrogen bonded into an infinite two dimensional network utilizing all OH protons.

Role of myo-inositol

Desymmetrization of 2,4,5,6-tetra-O-benzyl-D-myo-inositol for the synthesis of mycothiol.

An efficient chemical synthesis of mycothiol involving the regioselective ketopinyl desymmetrization of 2,4,5,6-tetrabenzylated D-myo-inositol as the key step is described. Together with a highly α-stereoselective D-glucosaminylation, the whole procedure was accomplished in eight steps with an overall yield of 40%.

Identification of a functional 2-keto-myo-inositol dehydratase gene of Sinorhizobium fredii USDA191 required for myo-inositol utilization.

Sinorhizobium fredii USDA191 is a Gram-negative bacterium capable of forming nitrogen-fixing nodules on soybean roots. The USDA191 idhA gene encoding myo-inositol dehydrogenase, an enzyme necessary for myo-inositol utilization, is known to be involved in competitive nodulation and nitrogen fixation. In Bacillus subtilis, myo-inositol dehydrogenase catalyzes the first step of the myo-inositol ca...

myo-Inositol metabolism in plants

The multifunctional position supplied by myo-inositol is emerging as a central feature in plant biochemistry and physiology. In this critique, attention is drawn to metabolic aspects and current assessment is made of manifold ways in which myo-inositol and its metabolic products impact growth and development. The fact that a unique enzyme, common to all eukaryotic organisms where such assessmen...